Semaphorin 3A mitigates lipopolysaccharide-induced chondrocyte inflammation, apoptosis and extracellular matrix degradation by binding to Neuropilin-1

Semaphorin 3A (SEMA3A) and its receptor neuropilin-1 (NRP-1) are expressed low in chondrocytes under stress, and overexpressing SEMA3A reduces pro-inflammatory cytokine release. This study was aimed at exploring whether SEMA3A participates in lipopolysaccharide (LPS)-induced chondrocyte inflammation...

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Bibliographic Details
Main Authors: Huiyu Zhang, Yue Lu, BingBing Wu, Fei Xia
Format: article
Language:EN
Published: Taylor & Francis Group 2021
Subjects:
Online Access:https://doaj.org/article/c02d831afe32491c914f6ea35536d584
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