LINC complex-Lis1 interplay controls MT1-MMP matrix digest-on-demand response for confined tumor cell migration

The ability of cancer cells to migrate through small, constricted areas is limited by nuclear stiffness. Here the authors show that in turn nuclear stiffness stimulates the delivery of enzymes important for the degradation of the extracellular matrix and the formation of invadopodia in association w...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Elvira Infante, Alessia Castagnino, Robin Ferrari, Pedro Monteiro, Sonia Agüera-González, Perrine Paul-Gilloteaux, Mélanie J. Domingues, Paolo Maiuri, Matthew Raab, Catherine M. Shanahan, Alexandre Baffet, Matthieu Piel, Edgar R. Gomes, Philippe Chavrier
Format: article
Langue:EN
Publié: Nature Portfolio 2018
Sujets:
Q
Accès en ligne:https://doaj.org/article/c03c4d3f6d774108a7eadc5798a2cc80
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!