Cryo-EM reveals the structural basis of microtubule depolymerization by kinesin-13s

Kinesin-13s are microtubule depolymerases that lack motile activity. Here the authors present the cryo-EM structures of kinesin-13 microtubule complexes in different nucleotide bound states, which reveal how ATP hydrolysis is linked to conformational changes and propose a model for kinesin induced d...

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Autores principales: Matthieu P.M.H. Benoit, Ana B. Asenjo, Hernando Sosa
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/c060d539f3bb453bab56271b9db5aab9
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