Variable number tandem repeats mediate the expression of proximal genes

Variable number tandem repeats mediate the expression of proximal genes

Variable number tandem repeats (VNTRs) are implicated in human diseases yet have been difficult to analyse computationally. Here, the authors describe a neural network method, adVNTR-NN, that allows rapid and accurate genotyping of VNTRs from large whole genome sequencing datasets.

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Autores principales: Mehrdad Bakhtiari, Jonghun Park, Yuan-Chun Ding, Sharona Shleizer-Burko, Susan L. Neuhausen, Bjarni V. Halldórsson, Kári Stefánsson, Melissa Gymrek, Vineet Bafna
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/c0620434d6a14d2c97241fa0db512255
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