The Mycobacterium tuberculosis FAS-II dehydratases and methyltransferases define the specificity of the mycolic acid elongation complexes.
<h4>Background</h4>The human pathogen Mycobacterium tuberculosis (Mtb) has the originality of possessing a multifunctional mega-enzyme FAS-I (Fatty Acid Synthase-I), together with a multi-protein FAS-II system, to carry out the biosynthesis of common and of specific long chain fatty acid...
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Main Authors: | Sylvain Cantaloube, Romain Veyron-Churlet, Nabila Haddache, Mamadou Daffé, Didier Zerbib |
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Format: | article |
Language: | EN |
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Public Library of Science (PLoS)
2011
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Online Access: | https://doaj.org/article/c068d5605e7d4b988c72f8814c5ec2cc |
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