A theoretical model of Polycomb/Trithorax action unites stable epigenetic memory and dynamic regulation

Polycomb (PcG) and Trithorax (TrxG) group regulate several hundred target genes with important roles in development and disease. Here the authors combine experiment and theory to provide evidence that the Polycomb/Trithorax system has the potential for a rich repertoire of regulatory modes beyond si...

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Auteurs principaux: Jeannette Reinig, Frank Ruge, Martin Howard, Leonie Ringrose
Format: article
Langue:EN
Publié: Nature Portfolio 2020
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Accès en ligne:https://doaj.org/article/c081d1c5a15a439ca97b4307c27e34a7
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