A theoretical model of Polycomb/Trithorax action unites stable epigenetic memory and dynamic regulation

A theoretical model of Polycomb/Trithorax action unites stable epigenetic memory and dynamic regulation

Polycomb (PcG) and Trithorax (TrxG) group regulate several hundred target genes with important roles in development and disease. Here the authors combine experiment and theory to provide evidence that the Polycomb/Trithorax system has the potential for a rich repertoire of regulatory modes beyond si...

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Autores principales: Jeannette Reinig, Frank Ruge, Martin Howard, Leonie Ringrose
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/c081d1c5a15a439ca97b4307c27e34a7
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spelling oai:doaj.org-article:c081d1c5a15a439ca97b4307c27e34a72021-12-02T15:14:56ZA theoretical model of Polycomb/Trithorax action unites stable epigenetic memory and dynamic regulation10.1038/s41467-020-18507-42041-1723https://doaj.org/article/c081d1c5a15a439ca97b4307c27e34a72020-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18507-4https://doaj.org/toc/2041-1723Polycomb (PcG) and Trithorax (TrxG) group regulate several hundred target genes with important roles in development and disease. Here the authors combine experiment and theory to provide evidence that the Polycomb/Trithorax system has the potential for a rich repertoire of regulatory modes beyond simple epigenetic memory.Jeannette ReinigFrank RugeMartin HowardLeonie RingroseNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Jeannette Reinig
Frank Ruge
Martin Howard
Leonie Ringrose
A theoretical model of Polycomb/Trithorax action unites stable epigenetic memory and dynamic regulation
description Polycomb (PcG) and Trithorax (TrxG) group regulate several hundred target genes with important roles in development and disease. Here the authors combine experiment and theory to provide evidence that the Polycomb/Trithorax system has the potential for a rich repertoire of regulatory modes beyond simple epigenetic memory.
format article
author Jeannette Reinig
Frank Ruge
Martin Howard
Leonie Ringrose
author_facet Jeannette Reinig
Frank Ruge
Martin Howard
Leonie Ringrose
author_sort Jeannette Reinig
title A theoretical model of Polycomb/Trithorax action unites stable epigenetic memory and dynamic regulation
title_short A theoretical model of Polycomb/Trithorax action unites stable epigenetic memory and dynamic regulation
title_full A theoretical model of Polycomb/Trithorax action unites stable epigenetic memory and dynamic regulation
title_fullStr A theoretical model of Polycomb/Trithorax action unites stable epigenetic memory and dynamic regulation
title_full_unstemmed A theoretical model of Polycomb/Trithorax action unites stable epigenetic memory and dynamic regulation
title_sort theoretical model of polycomb/trithorax action unites stable epigenetic memory and dynamic regulation
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/c081d1c5a15a439ca97b4307c27e34a7
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AT martinhoward atheoreticalmodelofpolycombtrithoraxactionunitesstableepigeneticmemoryanddynamicregulation
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AT jeannettereinig theoreticalmodelofpolycombtrithoraxactionunitesstableepigeneticmemoryanddynamicregulation
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