A theoretical model of Polycomb/Trithorax action unites stable epigenetic memory and dynamic regulation
Polycomb (PcG) and Trithorax (TrxG) group regulate several hundred target genes with important roles in development and disease. Here the authors combine experiment and theory to provide evidence that the Polycomb/Trithorax system has the potential for a rich repertoire of regulatory modes beyond si...
Guardado en:
Autores principales: | Jeannette Reinig, Frank Ruge, Martin Howard, Leonie Ringrose |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2020
|
Materias: | |
Acceso en línea: | https://doaj.org/article/c081d1c5a15a439ca97b4307c27e34a7 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Theoretical analysis of Polycomb-Trithorax systems predicts that poised chromatin is bistable and not bivalent
por: Kim Sneppen, et al.
Publicado: (2019) -
Functional conservation of Asxl2, a murine homolog for the Drosophila enhancer of trithorax and polycomb group gene Asx.
por: Heather A Baskind, et al.
Publicado: (2009) -
New partners in regulation of gene expression: the enhancer of Trithorax and Polycomb Corto interacts with methylated ribosomal protein l12 via its chromodomain.
por: Anne Coléno-Costes, et al.
Publicado: (2012) -
Theoretical Stable Hydraulic Section based on the Principle of Least Action
por: Noriaki Ohara, et al.
Publicado: (2019) -
Polycomb condensates can promote epigenetic marks but are not required for sustained chromatin compaction
por: Jorine M. Eeftens, et al.
Publicado: (2021)