The homeodomain-containing transcription factors Arx and Pax4 control enteroendocrine subtype specification in mice.

Intestinal hormones are key regulators of digestion and energy homeostasis secreted by rare enteroendocrine cells. These cells produce over ten different hormones including GLP-1 and GIP peptides known to promote insulin secretion. To date, the molecular mechanisms controlling the specification of t...

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Autores principales: Anthony Beucher, Elisabet Gjernes, Caitlin Collin, Monica Courtney, Aline Meunier, Patrick Collombat, Gérard Gradwohl
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/c0837999b685493384adbfd4041922c9
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