Exploiting collider bias to apply two-sample summary data Mendelian randomization methods to one-sample individual level data.
Over the last decade the availability of SNP-trait associations from genome-wide association studies has led to an array of methods for performing Mendelian randomization studies using only summary statistics. A common feature of these methods, besides their intuitive simplicity, is the ability to c...
Guardado en:
Autores principales: | Ciarrah Barry, Junxi Liu, Rebecca Richmond, Martin K Rutter, Deborah A Lawlor, Frank Dudbridge, Jack Bowden |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/c099838721364574958c3eb547906b95 |
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