A Poly-<italic toggle="yes">N</italic>-Acetylglucosamine−Shiga Toxin Broad-Spectrum Conjugate Vaccine for Shiga Toxin-Producing <named-content content-type="genus-species">Escherichia coli</named-content>

ABSTRACT Many pathogens produce the β-(1−6)-linked poly-N-acetylglucosamine (PNAG) surface polysaccharide that is being developed as a broadly protective antimicrobial vaccine. However, it is unknown whether systemically injected PNAG vaccines or antibodies would provide protective immunity against...

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Autores principales: Xi Lu, David Skurnik, Clarissa Pozzi, Damien Roux, Colette Cywes-Bentley, Jennifer M. Ritchie, Diana Munera, Marina L. Gening, Yury E. Tsvetkov, Nikolay E. Nifantiev, Matthew K. Waldor, Gerald B. Pier
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2014
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Acceso en línea:https://doaj.org/article/c0a6644caac94e5d8275ec36054581d6
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