Efficient hepatic differentiation and regeneration potential under xeno-free conditions using mass-producible amnion-derived mesenchymal stem cells

Efficient hepatic differentiation and regeneration potential under xeno-free conditions using mass-producible amnion-derived mesenchymal stem cells

Abstract Background Amnion-derived mesenchymal stem cells (AM-MSCs) are an attractive source of stem cell therapy for patients with irreversible liver disease. However, there are obstacles to their use due to low efficiency and xeno-contamination for hepatic differentiation. Methods We established a...

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Bibliographic Details
Main Authors: Jiwan Choi, Seoon Kang, Bitnara Kim, Seongjun So, Jongsuk Han, Gyeong-Nam Kim, Mi-Young Lee, Seonae Roh, Ji-Yoon Lee, Soo Jin Oh, Young Hoon Sung, Yeonmi Lee, Sung Hoon Kim, Eunju Kang
Format: article
Language:EN
Published: BMC 2021
Subjects:
Amnion-derived mesenchymal stem cells
Differentiation
Hepatic progenitor
Xeno-free
GSK3 inhibitor
Polyvinyl alcohol
Medicine (General)
R5-920
Biochemistry
QD415-436
Online Access:https://doaj.org/article/c0b94a38743f47e7ac643264d8cc10dd
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https://doaj.org/article/c0b94a38743f47e7ac643264d8cc10dd

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