L-type calcium channels regulate filopodia stability and cancer cell invasion downstream of integrin signalling
Filopodia have a prominent role in driving cancer cell invasion. Here, the authors show that L-type calcium channels are a druggable target regulating filopodia stability and maturation into focal adhesions in metastatic breast cancer cells.
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Auteurs principaux: | , , , , , , , , , , |
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Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2016
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Sujets: | |
Accès en ligne: | https://doaj.org/article/c0c5390a16a0498f861b5ea72324fa6a |
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