Ciclopirox inhibits Hepatitis B Virus secretion by blocking capsid assembly
Current treatments for chronic hepatitis B virus (HBV) infection are not curative. Here, the authors show that an antifungal drug, ciclopirox, inhibits HBV capsid assembly and synergizes with nucleoside/nucleotide analogs to prevent HBV replication in cells and in a humanized liver mouse model.
Enregistré dans:
Auteurs principaux: | , , , , , , , , , , , |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2019
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/c10c1a7e6f104a508eca916208b6abe6 |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|