Evolution of drift robustness in small populations
Genetic drift can reduce fitness in small populations by counteracting selection against deleterious mutations. Here, LaBar and Adami demonstrate through a mathematical model and simulations that small populations tend to evolve to drift-robust fitness peaks, which have a low likelihood of slightly-...
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Nature Portfolio
2017
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oai:doaj.org-article:c10d3c4803664beebf258eb3929722422021-12-02T14:42:40ZEvolution of drift robustness in small populations10.1038/s41467-017-01003-72041-1723https://doaj.org/article/c10d3c4803664beebf258eb3929722422017-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01003-7https://doaj.org/toc/2041-1723Genetic drift can reduce fitness in small populations by counteracting selection against deleterious mutations. Here, LaBar and Adami demonstrate through a mathematical model and simulations that small populations tend to evolve to drift-robust fitness peaks, which have a low likelihood of slightly-deleterious mutations.Thomas LaBarChristoph AdamiNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-12 (2017) |
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EN |
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Science Q |
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Science Q Thomas LaBar Christoph Adami Evolution of drift robustness in small populations |
description |
Genetic drift can reduce fitness in small populations by counteracting selection against deleterious mutations. Here, LaBar and Adami demonstrate through a mathematical model and simulations that small populations tend to evolve to drift-robust fitness peaks, which have a low likelihood of slightly-deleterious mutations. |
format |
article |
author |
Thomas LaBar Christoph Adami |
author_facet |
Thomas LaBar Christoph Adami |
author_sort |
Thomas LaBar |
title |
Evolution of drift robustness in small populations |
title_short |
Evolution of drift robustness in small populations |
title_full |
Evolution of drift robustness in small populations |
title_fullStr |
Evolution of drift robustness in small populations |
title_full_unstemmed |
Evolution of drift robustness in small populations |
title_sort |
evolution of drift robustness in small populations |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/c10d3c4803664beebf258eb392972242 |
work_keys_str_mv |
AT thomaslabar evolutionofdriftrobustnessinsmallpopulations AT christophadami evolutionofdriftrobustnessinsmallpopulations |
_version_ |
1718389657001000960 |