Evolution of drift robustness in small populations

Genetic drift can reduce fitness in small populations by counteracting selection against deleterious mutations. Here, LaBar and Adami demonstrate through a mathematical model and simulations that small populations tend to evolve to drift-robust fitness peaks, which have a low likelihood of slightly-...

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Autores principales: Thomas LaBar, Christoph Adami
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/c10d3c4803664beebf258eb392972242
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spelling oai:doaj.org-article:c10d3c4803664beebf258eb3929722422021-12-02T14:42:40ZEvolution of drift robustness in small populations10.1038/s41467-017-01003-72041-1723https://doaj.org/article/c10d3c4803664beebf258eb3929722422017-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01003-7https://doaj.org/toc/2041-1723Genetic drift can reduce fitness in small populations by counteracting selection against deleterious mutations. Here, LaBar and Adami demonstrate through a mathematical model and simulations that small populations tend to evolve to drift-robust fitness peaks, which have a low likelihood of slightly-deleterious mutations.Thomas LaBarChristoph AdamiNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Thomas LaBar
Christoph Adami
Evolution of drift robustness in small populations
description Genetic drift can reduce fitness in small populations by counteracting selection against deleterious mutations. Here, LaBar and Adami demonstrate through a mathematical model and simulations that small populations tend to evolve to drift-robust fitness peaks, which have a low likelihood of slightly-deleterious mutations.
format article
author Thomas LaBar
Christoph Adami
author_facet Thomas LaBar
Christoph Adami
author_sort Thomas LaBar
title Evolution of drift robustness in small populations
title_short Evolution of drift robustness in small populations
title_full Evolution of drift robustness in small populations
title_fullStr Evolution of drift robustness in small populations
title_full_unstemmed Evolution of drift robustness in small populations
title_sort evolution of drift robustness in small populations
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/c10d3c4803664beebf258eb392972242
work_keys_str_mv AT thomaslabar evolutionofdriftrobustnessinsmallpopulations
AT christophadami evolutionofdriftrobustnessinsmallpopulations
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