High sensitivity analysis of nanogram quantities of glycosaminoglycans using ToF-SIMS

Glycosaminoglycans are an important class of carbohydrates, but pose substantial analytical challenges. Here ToF-SIMS combined with multivariate analysis distinguishes six classes of glycosaminoglycans, including distinguishing heparin samples from different animal sources at a sensitivity as low as...

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Autores principales: Andrew L. Hook, John Hogwood, Elaine Gray, Barbara Mulloy, Catherine L. R. Merry
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/c121f4f95c754304b98a4975451b0470
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