Optimization of Initial Dose Regimen for Sirolimus in Pediatric Patients With Lymphangioma

Sirolimus is an effective oral treatment for pediatric patients with lymphangioma. The present clinical study in 15 children (0.12–16.39 years of age) examines the effects of underlying factors on sirolimus concentrations through application of a population pharmacokinetic model. Using Monte Carlo s...

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Autores principales: Xiao Chen, Dongdong Wang, Guangfei Wang, Yidie Huang, Xin Yu, Jinmiao Lu, Xiaowen Zhai, Hong Xu, Zhiping Li
Formato: article
Lenguaje:EN
Publicado: Frontiers Media S.A. 2021
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Acceso en línea:https://doaj.org/article/c13e6d3278264d2a93c807a78e5b9a71
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