Optimization of Initial Dose Regimen for Sirolimus in Pediatric Patients With Lymphangioma

Sirolimus is an effective oral treatment for pediatric patients with lymphangioma. The present clinical study in 15 children (0.12–16.39 years of age) examines the effects of underlying factors on sirolimus concentrations through application of a population pharmacokinetic model. Using Monte Carlo s...

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Bibliographic Details
Main Authors: Xiao Chen, Dongdong Wang, Guangfei Wang, Yidie Huang, Xin Yu, Jinmiao Lu, Xiaowen Zhai, Hong Xu, Zhiping Li
Format: article
Language:EN
Published: Frontiers Media S.A. 2021
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Online Access:https://doaj.org/article/c13e6d3278264d2a93c807a78e5b9a71
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