Activation of proline biosynthesis is critical to maintain glutamate homeostasis during acute methamphetamine exposure

Abstract Methamphetamine (METH) is a highly addictive psychostimulant that causes long-lasting effects in the brain and increases the risk of developing neurodegenerative diseases. The cellular and molecular effects of METH in the brain are functionally linked to alterations in glutamate levels. Des...

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Autores principales: Bobby Jones, Muthukumar Balasubramaniam, Joseph J. Lebowitz, Anne Taylor, Fernando Villalta, Habibeh Khoshbouei, Carrie Grueter, Brad Grueter, Chandravanu Dash, Jui Pandhare
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/c14ac558b3974efd995809baf00a9f90
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