The natural product magnolol as a lead structure for the development of potent cannabinoid receptor agonists.

Magnolol (4-allyl-2-(5-allyl-2-hydroxyphenyl)phenol), the main bioactive constituent of the medicinal plant Magnolia officinalis, and its main metabolite tetrahydromagnolol were recently found to activate cannabinoid (CB) receptors. We now investigated the structure-activity relationships of (tetrah...

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Autores principales: Alexander Fuchs, Viktor Rempel, Christa E Müller
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/c1793116671740df9aadfcc075109511
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