A viral microRNA down-regulates multiple cell cycle genes through mRNA 5'UTRs.

Global gene expression data combined with bioinformatic analysis provides strong evidence that mammalian miRNAs mediate repression of gene expression primarily through binding sites within the 3' untranslated region (UTR). Using RNA induced silencing complex immunoprecipitation (RISC-IP) techni...

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Auteurs principaux: Finn Grey, Rebecca Tirabassi, Heather Meyers, Guanming Wu, Shannon McWeeney, Lauren Hook, Jay A Nelson
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2010
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Accès en ligne:https://doaj.org/article/c1ba2ad74b4b4f7d9b8089c45232e559
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