Role of SCCmec type in resistance to the synergistic activity of oxacillin and cefoxitin in MRSA

Abstract β-lactam antibiotics target penicillin-binding proteins (PBPs) preventing peptidoglycan synthesis and this inhibition is circumvented in methicillin resistant Staphylococcus aureus (MRSA) strains through the expression of an additional PBP, named PBP2A. This enzyme is encoded by the mecA ge...

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Autores principales: Nathalie T. Reichmann, Mariana G. Pinho
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/c1c1b73a4ab645769d8870ad90f7cf3b
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