Migratory functionalization of unactivated alkyl bromides for construction of all-carbon quaternary centers via transposed tert-C-radicals

Formation of tertiary C(sp3)-C bonds is a formidable challenge due to steric interactions and low barriers for isomerization of intermediates. Here, the authors show a Ni-catalyzed migratory 3,3-difluoroallylation of unactivated alkyl bromides at remote tertiary carbon centers.

Guardado en:
Detalles Bibliográficos
Autores principales: Chuan Zhu, Ze-Yao Liu, Luning Tang, Heng Zhang, Yu-Feng Zhang, Patrick J. Walsh, Chao Feng
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
Materias:
Q
Acceso en línea:https://doaj.org/article/c1c1c6877e324880b55b8b6a26de7d25
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!