Synthesis and Antiproliferative Activity of 2,4,6,7-Tetrasubstituted-2<i>H</i>-pyrazolo[4,3-<i>c</i>]pyridines

Synthesis and Antiproliferative Activity of 2,4,6,7-Tetrasubstituted-2<i>H</i>-pyrazolo[4,3-<i>c</i>]pyridines

A library of 2,4,6,7-tetrasubstituted-2<i>H</i>-pyrazolo[4,3-<i>c</i>]pyridines was prepared from easily accessible 1-phenyl-3-(2-phenylethynyl)-1<i>H</i>-pyrazole-4-carbaldehyde via an iodine-mediated electrophilic cyclization of intermediate 4-(azidomethyl)-1-ph...

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Detalles Bibliográficos
Autores principales: Beatričė Razmienė, Eva Řezníčková, Vaida Dambrauskienė, Radek Ostruszka, Martin Kubala, Asta Žukauskaitė, Vladimír Kryštof, Algirdas Šačkus, Eglė Arbačiauskienė
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
Materias:
antiproliferation
cell death
cross-coupling
cycloiodination
pyrazole
pyridine
Organic chemistry
QD241-441
Acceso en línea:https://doaj.org/article/c1e5ffbbb6c3420e803de16af82fd513
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https://doaj.org/article/c1e5ffbbb6c3420e803de16af82fd513

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