Dysregulation of Blimp1 transcriptional repressor unleashes p130Cas/ErbB2 breast cancer invasion

Abstract ErbB2 overexpression is detected in approximately 20% of breast cancers and is correlated with poor survival. It was previously shown that the adaptor protein p130Cas/BCAR1 is a crucial mediator of ErbB2 transformation and that its overexpression confers invasive properties to ErbB2-positiv...

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Autores principales: Marianna Sciortino, Maria del Pilar Camacho-Leal, Francesca Orso, Elena Grassi, Andrea Costamagna, Paolo Provero, Wayne Tam, Emilia Turco, Paola Defilippi, Daniela Taverna, Sara Cabodi
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/c219a533573a4869ae802e7d793d8eef
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