Genetic mosaic dissection of candidate genes in mice using mosaic analysis with double markers

Summary: Mosaic analysis with double markers (MADM) technology enables the generation of genetic mosaic tissue in mice. MADM enables concomitant fluorescent cell labeling and introduction of a mutation of a gene of interest with single-cell resolution. This protocol highlights major steps for the ge...

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Autores principales: Nicole Amberg, Simon Hippenmeyer
Formato: article
Lenguaje:EN
Publicado: Elsevier 2021
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Acceso en línea:https://doaj.org/article/c226ec2616a248d788bc15a97b4f1626
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