Genetic mosaic dissection of candidate genes in mice using mosaic analysis with double markers

Summary: Mosaic analysis with double markers (MADM) technology enables the generation of genetic mosaic tissue in mice. MADM enables concomitant fluorescent cell labeling and introduction of a mutation of a gene of interest with single-cell resolution. This protocol highlights major steps for the ge...

Full description

Saved in:
Bibliographic Details
Main Authors: Nicole Amberg, Simon Hippenmeyer
Format: article
Language:EN
Published: Elsevier 2021
Subjects:
Online Access:https://doaj.org/article/c226ec2616a248d788bc15a97b4f1626
Tags: Add Tag
No Tags, Be the first to tag this record!