The Function of the Kynurenine Pathway in the Placenta: A Novel Pharmacotherapeutic Target?

(<i>L</i>-)tryptophan is metabolized via the kynurenine pathway into several kynurenine metabolites with distinct functions. Dysfunction of the kynurenine pathway can lead to impairments in vascular regulation, immune regulation, and tolerance. The first and rate limiting enzyme of this...

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Détails bibliographiques
Auteurs principaux: Michelle Broekhuizen, A. H. Jan Danser, Irwin K. M. Reiss, Daphne Merkus
Format: article
Langue:EN
Publié: MDPI AG 2021
Sujets:
R
Accès en ligne:https://doaj.org/article/c2520dc31aab497e8e697138f930e1ec
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