The Function of the Kynurenine Pathway in the Placenta: A Novel Pharmacotherapeutic Target?

(<i>L</i>-)tryptophan is metabolized via the kynurenine pathway into several kynurenine metabolites with distinct functions. Dysfunction of the kynurenine pathway can lead to impairments in vascular regulation, immune regulation, and tolerance. The first and rate limiting enzyme of this...

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Bibliographic Details
Main Authors: Michelle Broekhuizen, A. H. Jan Danser, Irwin K. M. Reiss, Daphne Merkus
Format: article
Language:EN
Published: MDPI AG 2021
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Online Access:https://doaj.org/article/c2520dc31aab497e8e697138f930e1ec
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