Expanding detection windows for discriminating single nucleotide variants using rationally designed DNA equalizer probes

The design of nucleic acid hybridisation probes is important for their use in DNA nanotechnology and biomedical applications. Here the authors use a DNA equalizer gate approach that expands the detection windows for improved sequence selectivity.

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Autores principales: Guan A. Wang, Xiaoyu Xie, Hayam Mansour, Fangfang Chen, Gabriela Matamoros, Ana L. Sanchez, Chunhai Fan, Feng Li
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/c25e94d7622a4e7ea1a8205c6f562036
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