Expanding detection windows for discriminating single nucleotide variants using rationally designed DNA equalizer probes

The design of nucleic acid hybridisation probes is important for their use in DNA nanotechnology and biomedical applications. Here the authors use a DNA equalizer gate approach that expands the detection windows for improved sequence selectivity.

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Bibliographic Details
Main Authors: Guan A. Wang, Xiaoyu Xie, Hayam Mansour, Fangfang Chen, Gabriela Matamoros, Ana L. Sanchez, Chunhai Fan, Feng Li
Format: article
Language:EN
Published: Nature Portfolio 2020
Subjects:
Q
Online Access:https://doaj.org/article/c25e94d7622a4e7ea1a8205c6f562036
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