Expanding detection windows for discriminating single nucleotide variants using rationally designed DNA equalizer probes

The design of nucleic acid hybridisation probes is important for their use in DNA nanotechnology and biomedical applications. Here the authors use a DNA equalizer gate approach that expands the detection windows for improved sequence selectivity.

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Autores principales:	Guan A. Wang, Xiaoyu Xie, Hayam Mansour, Fangfang Chen, Gabriela Matamoros, Ana L. Sanchez, Chunhai Fan, Feng Li
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/c25e94d7622a4e7ea1a8205c6f562036
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spelling	oai:doaj.org-article:c25e94d7622a4e7ea1a8205c6f5620362021-12-02T17:32:43ZExpanding detection windows for discriminating single nucleotide variants using rationally designed DNA equalizer probes10.1038/s41467-020-19269-92041-1723https://doaj.org/article/c25e94d7622a4e7ea1a8205c6f5620362020-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19269-9https://doaj.org/toc/2041-1723The design of nucleic acid hybridisation probes is important for their use in DNA nanotechnology and biomedical applications. Here the authors use a DNA equalizer gate approach that expands the detection windows for improved sequence selectivity.Guan A. WangXiaoyu XieHayam MansourFangfang ChenGabriela MatamorosAna L. SanchezChunhai FanFeng LiNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Guan A. Wang Xiaoyu Xie Hayam Mansour Fangfang Chen Gabriela Matamoros Ana L. Sanchez Chunhai Fan Feng Li Expanding detection windows for discriminating single nucleotide variants using rationally designed DNA equalizer probes
description	The design of nucleic acid hybridisation probes is important for their use in DNA nanotechnology and biomedical applications. Here the authors use a DNA equalizer gate approach that expands the detection windows for improved sequence selectivity.
format	article
author	Guan A. Wang Xiaoyu Xie Hayam Mansour Fangfang Chen Gabriela Matamoros Ana L. Sanchez Chunhai Fan Feng Li
author_facet	Guan A. Wang Xiaoyu Xie Hayam Mansour Fangfang Chen Gabriela Matamoros Ana L. Sanchez Chunhai Fan Feng Li
author_sort	Guan A. Wang
title	Expanding detection windows for discriminating single nucleotide variants using rationally designed DNA equalizer probes
title_short	Expanding detection windows for discriminating single nucleotide variants using rationally designed DNA equalizer probes
title_full	Expanding detection windows for discriminating single nucleotide variants using rationally designed DNA equalizer probes
title_fullStr	Expanding detection windows for discriminating single nucleotide variants using rationally designed DNA equalizer probes
title_full_unstemmed	Expanding detection windows for discriminating single nucleotide variants using rationally designed DNA equalizer probes
title_sort	expanding detection windows for discriminating single nucleotide variants using rationally designed dna equalizer probes
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/c25e94d7622a4e7ea1a8205c6f562036
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Expanding detection windows for discriminating single nucleotide variants using rationally designed DNA equalizer probes

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