Expanding detection windows for discriminating single nucleotide variants using rationally designed DNA equalizer probes
The design of nucleic acid hybridisation probes is important for their use in DNA nanotechnology and biomedical applications. Here the authors use a DNA equalizer gate approach that expands the detection windows for improved sequence selectivity.
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Main Authors: | Guan A. Wang, Xiaoyu Xie, Hayam Mansour, Fangfang Chen, Gabriela Matamoros, Ana L. Sanchez, Chunhai Fan, Feng Li |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2020
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Subjects: | |
Online Access: | https://doaj.org/article/c25e94d7622a4e7ea1a8205c6f562036 |
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