Functional impact of cytochrome P450 3A (CYP3A) missense variants in cattle

Functional impact of cytochrome P450 3A (CYP3A) missense variants in cattle

Abstract Cytochrome P450 3A is the most important CYP subfamily in humans, and CYP3A4/CYP3A5 genetic variants contribute to inter-individual variability in drug metabolism. However, no information is available for bovine CYP3A (bCYP3A). Here we described bCYP3A missense single nucleotide variants (S...

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Auteurs principaux: Mery Giantin, Minna Rahnasto-Rilla, Roberta Tolosi, Lorena Lucatello, Marianna Pauletto, Giorgia Guerra, Francesca Pezzato, Rosa M. Lopparelli, Roberta Merlanti, Paolo Carnier, Francesca Capolongo, Paavo Honkakoski, Mauro Dacasto
Format: article
Langue:EN
Publié: Nature Portfolio 2019
Sujets:
Medicine
R
Science
Q
Accès en ligne:https://doaj.org/article/c25ec162a21642f68798b8d5ca6a8b2b
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https://doaj.org/article/c25ec162a21642f68798b8d5ca6a8b2b

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