Single-cell mutation identification via phylogenetic inference

Cross-cell heterogeneity of genotypes can be revealed by analyzing single-cell sequencing data. Here the authors develop a tool for single-cell variant calling via phylogenetic inference, and use it to analyze cancer genomics datasets.

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Bibliographic Details
Main Authors: Jochen Singer, Jack Kuipers, Katharina Jahn, Niko Beerenwinkel
Format: article
Language:EN
Published: Nature Portfolio 2018
Subjects:
Q
Online Access:https://doaj.org/article/c27e9efdc03843eda0fe4c408b3ec786
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