Single-cell mutation identification via phylogenetic inference

Cross-cell heterogeneity of genotypes can be revealed by analyzing single-cell sequencing data. Here the authors develop a tool for single-cell variant calling via phylogenetic inference, and use it to analyze cancer genomics datasets.

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Detalles Bibliográficos
Autores principales:	Jochen Singer, Jack Kuipers, Katharina Jahn, Niko Beerenwinkel
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/c27e9efdc03843eda0fe4c408b3ec786
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id	oai:doaj.org-article:c27e9efdc03843eda0fe4c408b3ec786
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spelling	oai:doaj.org-article:c27e9efdc03843eda0fe4c408b3ec7862021-12-02T15:33:59ZSingle-cell mutation identification via phylogenetic inference10.1038/s41467-018-07627-72041-1723https://doaj.org/article/c27e9efdc03843eda0fe4c408b3ec7862018-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07627-7https://doaj.org/toc/2041-1723Cross-cell heterogeneity of genotypes can be revealed by analyzing single-cell sequencing data. Here the authors develop a tool for single-cell variant calling via phylogenetic inference, and use it to analyze cancer genomics datasets.Jochen SingerJack KuipersKatharina JahnNiko BeerenwinkelNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-8 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jochen Singer Jack Kuipers Katharina Jahn Niko Beerenwinkel Single-cell mutation identification via phylogenetic inference
description	Cross-cell heterogeneity of genotypes can be revealed by analyzing single-cell sequencing data. Here the authors develop a tool for single-cell variant calling via phylogenetic inference, and use it to analyze cancer genomics datasets.
format	article
author	Jochen Singer Jack Kuipers Katharina Jahn Niko Beerenwinkel
author_facet	Jochen Singer Jack Kuipers Katharina Jahn Niko Beerenwinkel
author_sort	Jochen Singer
title	Single-cell mutation identification via phylogenetic inference
title_short	Single-cell mutation identification via phylogenetic inference
title_full	Single-cell mutation identification via phylogenetic inference
title_fullStr	Single-cell mutation identification via phylogenetic inference
title_full_unstemmed	Single-cell mutation identification via phylogenetic inference
title_sort	single-cell mutation identification via phylogenetic inference
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/c27e9efdc03843eda0fe4c408b3ec786
work_keys_str_mv	AT jochensinger singlecellmutationidentificationviaphylogeneticinference AT jackkuipers singlecellmutationidentificationviaphylogeneticinference AT katharinajahn singlecellmutationidentificationviaphylogeneticinference AT nikobeerenwinkel singlecellmutationidentificationviaphylogeneticinference
_version_	1718386989440434176

Single-cell mutation identification via phylogenetic inference

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