Single-cell mutation identification via phylogenetic inference
Cross-cell heterogeneity of genotypes can be revealed by analyzing single-cell sequencing data. Here the authors develop a tool for single-cell variant calling via phylogenetic inference, and use it to analyze cancer genomics datasets.
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Autores principales: | Jochen Singer, Jack Kuipers, Katharina Jahn, Niko Beerenwinkel |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2018
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Materias: | |
Acceso en línea: | https://doaj.org/article/c27e9efdc03843eda0fe4c408b3ec786 |
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