Interferon Lambda Signaling in Macrophages Is Necessary for the Antiviral Response to Influenza

Interferon lambda (IFNλ) signaling is a promising therapeutic target against viral infection in murine models, yet little is known about its molecular regulation and its cognate receptor, interferon lambda receptor 1 (IFNLR1) in human lung. We hypothesized that the IFNλ signaling axis was active in...

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Auteurs principaux: Rama K. Mallampalli, Jessica Adair, Ajit Elhance, Daniela Farkas, Lexie Chafin, Matthew E. Long, Mithu De, Ana L. Mora, Mauricio Rojas, Victor Peters, Joseph S. Bednash, MuChun Tsai, James D. Londino
Format: article
Langue:EN
Publié: Frontiers Media S.A. 2021
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Accès en ligne:https://doaj.org/article/c2a4910660b74ab6bd0cf80dde1bc0a3
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