Interferon Lambda Signaling in Macrophages Is Necessary for the Antiviral Response to Influenza
Interferon lambda (IFNλ) signaling is a promising therapeutic target against viral infection in murine models, yet little is known about its molecular regulation and its cognate receptor, interferon lambda receptor 1 (IFNLR1) in human lung. We hypothesized that the IFNλ signaling axis was active in...
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Autores principales: | Rama K. Mallampalli, Jessica Adair, Ajit Elhance, Daniela Farkas, Lexie Chafin, Matthew E. Long, Mithu De, Ana L. Mora, Mauricio Rojas, Victor Peters, Joseph S. Bednash, MuChun Tsai, James D. Londino |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/c2a4910660b74ab6bd0cf80dde1bc0a3 |
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