G9a regulates breast cancer growth by modulating iron homeostasis through the repression of ferroxidase hephaestin

G9a is a histone methyltransferase highly expressed in several cancers including breast cancer. Here the authors propose a mechanism through which G9a promotes breast cancer by regulating iron metabolism through the repression of ferroxidase hephaestin.

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Auteurs principaux: Ya-fang Wang, Jie Zhang, Yi Su, Yan-yan Shen, Dong-xian Jiang, Ying-yong Hou, Mei-yu Geng, Jian Ding, Yi Chen
Format: article
Langue:EN
Publié: Nature Portfolio 2017
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Accès en ligne:https://doaj.org/article/c2b4a30f130740a69c6fdad77d98f0fb
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