G9a regulates breast cancer growth by modulating iron homeostasis through the repression of ferroxidase hephaestin
G9a is a histone methyltransferase highly expressed in several cancers including breast cancer. Here the authors propose a mechanism through which G9a promotes breast cancer by regulating iron metabolism through the repression of ferroxidase hephaestin.
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Nature Portfolio
2017
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oai:doaj.org-article:c2b4a30f130740a69c6fdad77d98f0fb2021-12-02T10:48:10ZG9a regulates breast cancer growth by modulating iron homeostasis through the repression of ferroxidase hephaestin10.1038/s41467-017-00350-92041-1723https://doaj.org/article/c2b4a30f130740a69c6fdad77d98f0fb2017-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00350-9https://doaj.org/toc/2041-1723G9a is a histone methyltransferase highly expressed in several cancers including breast cancer. Here the authors propose a mechanism through which G9a promotes breast cancer by regulating iron metabolism through the repression of ferroxidase hephaestin.Ya-fang WangJie ZhangYi SuYan-yan ShenDong-xian JiangYing-yong HouMei-yu GengJian DingYi ChenNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-14 (2017) |
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Science Q Ya-fang Wang Jie Zhang Yi Su Yan-yan Shen Dong-xian Jiang Ying-yong Hou Mei-yu Geng Jian Ding Yi Chen G9a regulates breast cancer growth by modulating iron homeostasis through the repression of ferroxidase hephaestin |
description |
G9a is a histone methyltransferase highly expressed in several cancers including breast cancer. Here the authors propose a mechanism through which G9a promotes breast cancer by regulating iron metabolism through the repression of ferroxidase hephaestin. |
format |
article |
author |
Ya-fang Wang Jie Zhang Yi Su Yan-yan Shen Dong-xian Jiang Ying-yong Hou Mei-yu Geng Jian Ding Yi Chen |
author_facet |
Ya-fang Wang Jie Zhang Yi Su Yan-yan Shen Dong-xian Jiang Ying-yong Hou Mei-yu Geng Jian Ding Yi Chen |
author_sort |
Ya-fang Wang |
title |
G9a regulates breast cancer growth by modulating iron homeostasis through the repression of ferroxidase hephaestin |
title_short |
G9a regulates breast cancer growth by modulating iron homeostasis through the repression of ferroxidase hephaestin |
title_full |
G9a regulates breast cancer growth by modulating iron homeostasis through the repression of ferroxidase hephaestin |
title_fullStr |
G9a regulates breast cancer growth by modulating iron homeostasis through the repression of ferroxidase hephaestin |
title_full_unstemmed |
G9a regulates breast cancer growth by modulating iron homeostasis through the repression of ferroxidase hephaestin |
title_sort |
g9a regulates breast cancer growth by modulating iron homeostasis through the repression of ferroxidase hephaestin |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/c2b4a30f130740a69c6fdad77d98f0fb |
work_keys_str_mv |
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