G9a regulates breast cancer growth by modulating iron homeostasis through the repression of ferroxidase hephaestin

G9a is a histone methyltransferase highly expressed in several cancers including breast cancer. Here the authors propose a mechanism through which G9a promotes breast cancer by regulating iron metabolism through the repression of ferroxidase hephaestin.

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Autores principales: Ya-fang Wang, Jie Zhang, Yi Su, Yan-yan Shen, Dong-xian Jiang, Ying-yong Hou, Mei-yu Geng, Jian Ding, Yi Chen
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/c2b4a30f130740a69c6fdad77d98f0fb
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spelling oai:doaj.org-article:c2b4a30f130740a69c6fdad77d98f0fb2021-12-02T10:48:10ZG9a regulates breast cancer growth by modulating iron homeostasis through the repression of ferroxidase hephaestin10.1038/s41467-017-00350-92041-1723https://doaj.org/article/c2b4a30f130740a69c6fdad77d98f0fb2017-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00350-9https://doaj.org/toc/2041-1723G9a is a histone methyltransferase highly expressed in several cancers including breast cancer. Here the authors propose a mechanism through which G9a promotes breast cancer by regulating iron metabolism through the repression of ferroxidase hephaestin.Ya-fang WangJie ZhangYi SuYan-yan ShenDong-xian JiangYing-yong HouMei-yu GengJian DingYi ChenNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Ya-fang Wang
Jie Zhang
Yi Su
Yan-yan Shen
Dong-xian Jiang
Ying-yong Hou
Mei-yu Geng
Jian Ding
Yi Chen
G9a regulates breast cancer growth by modulating iron homeostasis through the repression of ferroxidase hephaestin
description G9a is a histone methyltransferase highly expressed in several cancers including breast cancer. Here the authors propose a mechanism through which G9a promotes breast cancer by regulating iron metabolism through the repression of ferroxidase hephaestin.
format article
author Ya-fang Wang
Jie Zhang
Yi Su
Yan-yan Shen
Dong-xian Jiang
Ying-yong Hou
Mei-yu Geng
Jian Ding
Yi Chen
author_facet Ya-fang Wang
Jie Zhang
Yi Su
Yan-yan Shen
Dong-xian Jiang
Ying-yong Hou
Mei-yu Geng
Jian Ding
Yi Chen
author_sort Ya-fang Wang
title G9a regulates breast cancer growth by modulating iron homeostasis through the repression of ferroxidase hephaestin
title_short G9a regulates breast cancer growth by modulating iron homeostasis through the repression of ferroxidase hephaestin
title_full G9a regulates breast cancer growth by modulating iron homeostasis through the repression of ferroxidase hephaestin
title_fullStr G9a regulates breast cancer growth by modulating iron homeostasis through the repression of ferroxidase hephaestin
title_full_unstemmed G9a regulates breast cancer growth by modulating iron homeostasis through the repression of ferroxidase hephaestin
title_sort g9a regulates breast cancer growth by modulating iron homeostasis through the repression of ferroxidase hephaestin
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/c2b4a30f130740a69c6fdad77d98f0fb
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