REST regulation of gene networks in adult neural stem cells

The transcription factor REST plays a crucial role in maintaining the adult neural stem cell pool. To better understand how REST maintains quiescence in neural progenitors, the authors use ChIP-seq and RNA-seq and find that REST regulates represses ribosome biogenesis, cell cycle and neuronal genes.

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Autores principales: Shradha Mukherjee, Rebecca Brulet, Ling Zhang, Jenny Hsieh
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/c2c81079c07d4b48b6c984d8310c2a00
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