REST regulation of gene networks in adult neural stem cells

The transcription factor REST plays a crucial role in maintaining the adult neural stem cell pool. To better understand how REST maintains quiescence in neural progenitors, the authors use ChIP-seq and RNA-seq and find that REST regulates represses ribosome biogenesis, cell cycle and neuronal genes.

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Detalles Bibliográficos
Autores principales:	Shradha Mukherjee, Rebecca Brulet, Ling Zhang, Jenny Hsieh
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/c2c81079c07d4b48b6c984d8310c2a00
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spelling	oai:doaj.org-article:c2c81079c07d4b48b6c984d8310c2a002021-12-02T16:49:58ZREST regulation of gene networks in adult neural stem cells10.1038/ncomms133602041-1723https://doaj.org/article/c2c81079c07d4b48b6c984d8310c2a002016-11-01T00:00:00Zhttps://doi.org/10.1038/ncomms13360https://doaj.org/toc/2041-1723The transcription factor REST plays a crucial role in maintaining the adult neural stem cell pool. To better understand how REST maintains quiescence in neural progenitors, the authors use ChIP-seq and RNA-seq and find that REST regulates represses ribosome biogenesis, cell cycle and neuronal genes.Shradha MukherjeeRebecca BruletLing ZhangJenny HsiehNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Shradha Mukherjee Rebecca Brulet Ling Zhang Jenny Hsieh REST regulation of gene networks in adult neural stem cells
description	The transcription factor REST plays a crucial role in maintaining the adult neural stem cell pool. To better understand how REST maintains quiescence in neural progenitors, the authors use ChIP-seq and RNA-seq and find that REST regulates represses ribosome biogenesis, cell cycle and neuronal genes.
format	article
author	Shradha Mukherjee Rebecca Brulet Ling Zhang Jenny Hsieh
author_facet	Shradha Mukherjee Rebecca Brulet Ling Zhang Jenny Hsieh
author_sort	Shradha Mukherjee
title	REST regulation of gene networks in adult neural stem cells
title_short	REST regulation of gene networks in adult neural stem cells
title_full	REST regulation of gene networks in adult neural stem cells
title_fullStr	REST regulation of gene networks in adult neural stem cells
title_full_unstemmed	REST regulation of gene networks in adult neural stem cells
title_sort	rest regulation of gene networks in adult neural stem cells
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/c2c81079c07d4b48b6c984d8310c2a00
work_keys_str_mv	AT shradhamukherjee restregulationofgenenetworksinadultneuralstemcells AT rebeccabrulet restregulationofgenenetworksinadultneuralstemcells AT lingzhang restregulationofgenenetworksinadultneuralstemcells AT jennyhsieh restregulationofgenenetworksinadultneuralstemcells
_version_	1718383182675443712

REST regulation of gene networks in adult neural stem cells

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