REST regulation of gene networks in adult neural stem cells
The transcription factor REST plays a crucial role in maintaining the adult neural stem cell pool. To better understand how REST maintains quiescence in neural progenitors, the authors use ChIP-seq and RNA-seq and find that REST regulates represses ribosome biogenesis, cell cycle and neuronal genes.
Guardado en:
Autores principales: | Shradha Mukherjee, Rebecca Brulet, Ling Zhang, Jenny Hsieh |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2016
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Materias: | |
Acceso en línea: | https://doaj.org/article/c2c81079c07d4b48b6c984d8310c2a00 |
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