Rac1-regulated endothelial radiation response stimulates extravasation and metastasis that can be blocked by HMG-CoA reductase inhibitors.

Radiotherapy (RT) plays a key role in cancer treatment. Although the benefit of ionizing radiation (IR) is well established, some findings raise the possibility that irradiation of the primary tumor not only triggers a killing response but also increases the metastatic potential of surviving tumor c...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Melanie Hamalukic, Johannes Huelsenbeck, Arno Schad, Stefan Wirtz, Bernd Kaina, Gerhard Fritz
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2011
Materias:
R
Q
Acceso en línea:https://doaj.org/article/c2e52461860349a28e44f53b3579f5a2
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!