Asynchronous fate decisions by single cells collectively ensure consistent lineage composition in the mouse blastocyst

Early embryonic cell fate and lineage specification is tightly regulated in the preimplantation mammalian embryo. Here, the authors quantitatively examine the ratio of epiblast to primitive endoderm lineages in the blastocyst and show composition of the inner cell mass is conserved, independent of i...

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Autores principales: Néstor Saiz, Kiah M. Williams, Venkatraman E. Seshan, Anna-Katerina Hadjantonakis
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/c2f12aea656245e49a6337f8fa0848fb
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