Chemical genetics reveals bacterial and host cell functions critical for type IV effector translocation by Legionella pneumophila.

Delivery of effector proteins is a process widely used by bacterial pathogens to subvert host cell functions and cause disease. Effector delivery is achieved by elaborate injection devices and can often be triggered by environmental stimuli. However, effector export by the L. pneumophila Icm/Dot Typ...

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Autores principales: Xavier Charpentier, Joëlle E Gabay, Moraima Reyes, Jing W Zhu, Arthur Weiss, Howard A Shuman
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2009
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Acceso en línea:https://doaj.org/article/c2fb3b75d8864413b3670cb4e066a45a
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