Human-specific histone methylation signatures at transcription start sites in prefrontal neurons.

Human-specific histone methylation signatures at transcription start sites in prefrontal neurons.

Cognitive abilities and disorders unique to humans are thought to result from adaptively driven changes in brain transcriptomes, but little is known about the role of cis-regulatory changes affecting transcription start sites (TSS). Here, we mapped in human, chimpanzee, and macaque prefrontal cortex...

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Bibliographic Details
Main Authors: Hennady P Shulha, Jessica L Crisci, Denis Reshetov, Jogender S Tushir, Iris Cheung, Rahul Bharadwaj, Hsin-Jung Chou, Isaac B Houston, Cyril J Peter, Amanda C Mitchell, Wei-Dong Yao, Richard H Myers, Jiang-Fan Chen, Todd M Preuss, Evgeny I Rogaev, Jeffrey D Jensen, Zhiping Weng, Schahram Akbarian
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2012
Subjects:
Biology (General)
QH301-705.5
Online Access:https://doaj.org/article/c30b9fddce6b4bb48ac08d60aa858ebe
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