Bioluminescence imaging of G protein-coupled receptor activation in living mice

G protein-coupled receptors are involved in numerous physiological functions, thus, they represent potential pharmaceutical targets. Here Kono et al. describe a new mouse model to image GPCR activation in real-time by exploiting firefly split luciferase fragment complementation that can be detected...

Full description

Saved in:
Bibliographic Details
Main Authors: Mari Kono, Elizabeth G. Conlon, Samantha Y. Lux, Keisuke Yanagida, Timothy Hla, Richard L. Proia
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
Q
Online Access:https://doaj.org/article/c32511cc563843f48d30e2af1c4c9730
Tags: Add Tag
No Tags, Be the first to tag this record!