Bioluminescence imaging of G protein-coupled receptor activation in living mice

Bioluminescence imaging of G protein-coupled receptor activation in living mice

G protein-coupled receptors are involved in numerous physiological functions, thus, they represent potential pharmaceutical targets. Here Kono et al. describe a new mouse model to image GPCR activation in real-time by exploiting firefly split luciferase fragment complementation that can be detected...

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Autores principales: Mari Kono, Elizabeth G. Conlon, Samantha Y. Lux, Keisuke Yanagida, Timothy Hla, Richard L. Proia
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Science
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Acceso en línea:https://doaj.org/article/c32511cc563843f48d30e2af1c4c9730
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