Sterol targeting drugs reveal life cycle stage-specific differences in trypanosome lipid rafts

Abstract Cilia play important roles in cell signaling, facilitated by the unique lipid environment of a ciliary membrane containing high concentrations of sterol-rich lipid rafts. The African trypanosome Trypanosoma brucei is a single-celled eukaryote with a single cilium/flagellum. We tested whethe...

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Autores principales: Aabha I. Sharma, Cheryl L. Olson, João I. Mamede, Felipe Gazos-Lopes, Conrad L. Epting, Igor C. Almeida, David M. Engman
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/c329ff680ea940cfbaf9daa2d9cbf096
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